Prof. Dr. rer. nat. Christoph Syldatk

Prof. Dr. rer. nat. Christoph Syldatk

  • Institut für Bio- und Lebensmitteltechnik
    Teilinstitut 2: Technische Biologie
    Karlsruher Institut für Technologie (KIT)
    Gebäude 30.43
    Fritz-Haber-Weg 4
    76131 Karlsruhe

    Postadresse:
    Kaiserstr. 12
    76131 Karlsruhe

     

Curriculum Vitae

1976 – 1981 Study of Biology at the Technical University of Braunschweig (FRG)
1981 – 1984 Ph.D.-thesis on production and characterization of microbial biosurfactants in the group of Prof. Dr. Fritz Wagner; scientific co-worker at the Institute of Biochemistry and Biotechnology of the TU Braunschweig (FRG)
1985 – 1990 Assistant Professor at the Institute of Biochemistry and Biotechnology of the TU Braunschweig (FRG) and head of the newly formed research group "Regio- and stereoselective bioconversions"; research on bioconversions of cyclic amides (cooperation with Prof. Dr. Fritz Wagner and Prof. Dr. Karsten Krohn) and of silicon organic compounds (cooperation with Prof. Dr. Reinhold Tacke)
1989 Research stay at the Agricultural University in Wageningen (NL) in the group "Industrial Microbiology" of Prof. Dr. i.r. Jan de Bont (Industrial Microbiology); research on epoxide degrading enzymes
1990 Habilitation on the topic "Microbial hydantoin metabolism"
1990 – 1991 Lecturer at the Institute of Biochemistry and Biotechnology of the TU Braunschweig (FRG)
1991 – 1993 Heisenberg scholarship of the German Science Foundation (DFG)
1993 – 2004 Full Professor at the Institute of Biochemical Engineering of the University of Stuttgart (FRG) (Working area of Physiological Microbiology)
2000 Research stay monthes at the University of Kent at Canterbury (UKC) (UK) in the group "Microbial Technology" of Prof. Dr. Alan T. Bull; research on nitrile degrading microorganisms
Since 8/2003 Full Professor at the Institute für Bio- und Lebensmitteltechnik, Chair of "Technical Biology" in the Department of Chemical Engineering at the University of Karlsruhe/FRG
2004 - 2008 Nomination as member of the DECHEMA-Commission “Techniques of Biological Processes”
Since 11/2008 Chairman of the newly formed joint commission “Biotransformation” of the DECHEMA and VAAM
2008 – 2010 Vice Dean for Education of the Faculty of Chemical Engineering of the Karlsruhe Institute of Technology (KIT)
2010 - 2012 Dean of the Faculty of Chemical Engineering of the Karlsruhe Institute of Technology (KIT)
2010 Speaker of the  joint commission “Biotransformation” of the DECHEMA and VAAM
2012-2014 Vice Dean for Education of the Faculty of Chemical Engineering of the Karlsruhe Institute of Technology (KIT)

Memberships in vocational societies:

  • DECHEMA (German Society for Chemical Technology and Biotechnology)
  • VAAM (German Society for General and Applied Microbiology)
  • DGF (German Society for Fat Sciences)

Special activities:

Since 3/1996 Co-chairman of the VAAM-Working Group "Microbial Biotransformations"
Since 7/1996 Member of the Editorial Board of Biotechnology Letters
Since 3/1999 Nominated by the DECHEMA as German Delegate for the EFB-Working party "Education"
1996 – 1999 Chairman of the BMBF-joint-project "A cascade of enzymes for production of non-proteinogenic L-amino acids"
1999 – 2000 Member of the DECHEMA-Ad-Hoc-Commission "Recommendations for the Education in Biotechnology in Germany"
Since 2/2004 Member of the DECHEMA-Working Party "Techniques of Biological Processes"

Number of publications:

ca. 200 — of that 88 reported original papers and 18 patents

Research areas of interest:

Screening for new biocatalysts, bioreactor cultivation of microorganisms, immobilization of whole cells and isolated enzymes, enzyme technology, down stream processing, cyclic amidases, biosurfactants

Publications


2024
Intensification of biocatalytic processes by using alternative reaction media
Delavault, A.; Ochsenreither, K.; Syldatk, C.
2024. Physical Sciences Reviews, 9 (9), 2875–2897. doi:10.1515/psr-2022-0104
Intensification of Enzymatic Sorbityl Laurate Production in Dissolved and Neat Systems under Conventional and Microwave Heating
Delavault, A.; Opochenska, O.; Schönrock, S.; Hollenbach, R.; Ochsenreither, K.; Syldatk, C.
2024. ACS Omega, 9 (15), 17163–17173. doi:10.1021/acsomega.3c10004
2022
Enzymatic Synthesis of Alkyl Glucosides by β‐Glucosidases in a 2‐in‐1 Deep Eutectic Solvent System 
Delavault, A.; Grüninger, J.; Kapp, D.; Hollenbach, R.; Rudat, J.; Ochsenreither, K.; Syldatk, C.
2022. Chemie - Ingenieur - Technik, 94 (3), 417–426. doi:10.1002/cite.202100150
Enhanced Bioactivity of Tailor-Made Glycolipid Enriched Manuka Honey
Delavault, A.; Zoheir, A. E.; Muller, D.; Hollenbach, R.; Rabe, K. S.; Ochsenreither, K.; Rudat, J.; Syldatk, C.
2022. International Journal of Molecular Sciences, 23 (19), Art.-Nr.: 12031. doi:10.3390/ijms231912031
Lipase-Mediated Mechanoenzymatic Synthesis of Sugar Esters in Dissolved Unconventional and Neat Reaction Systems
Hollenbach, R.; Delavault, A.; Gebhardt, L.; Soergel, H.; Muhle-Goll, C.; Ochsenreither, K.; Syldatk, C.
2022. ACS Sustainable Chemistry & Engineering, 10 (31), 10192–10202. doi:10.1021/acssuschemeng.2c01727
Continuous Flow Glycolipid Synthesis Using a Packed Bed Reactor
Hollenbach, R.; Muller, D.; Delavault, A.; Syldatk, C.
2022. Catalysts, 12 (5), Art.-Nr. 551. doi:10.3390/catal12050551
2021
Lipase-Catalyzed Production of Sorbitol Laurate in a “2-in-1” Deep Eutectic System: Factors Affecting the Synthesis and Scalability
Delavault, A.; Opochenska, O.; Laneque, L.; Soergel, H.; Muhle-Goll, C.; Ochsenreither, K.; Syldatk, C.
2021. Molecules, 26 (9), 2759. doi:10.3390/molecules26092759
Controlled Adhesion of HUVEC on Polyelectrolyte Multilayers by Regulation of Coating Conditions
Rudt, A.; Sun, J.; Qin, M.; Liu, L.; Syldatk, C.; Barbeck, M.; Xiong, X.; Krastev, R.
2021. ACS applied bio materials, 4 (2), 1441–1449. doi:10.1021/acsabm.0c01330
Microwave-Assisted One-Pot Lipid Extraction and Glycolipid Production from Oleaginous Yeast Saitozyma podzolica in Sugar Alcohol-Based Media
Delavault, A.; Ochs, K.; Gorte, O.; Syldatk, C.; Durand, E.; Ochsenreither, K.
2021. Molecules (Basel, Switzerland), 26 (2), Art.-Nr. 470. doi:10.3390/molecules26020470
Comparative study on interfacial and foaming properties of glycolipids in relation to the gas applied for foam generation
Hollenbach, R.; Oeppling, S.; Delavault, A.; Völp, A. R.; Willenbacher, N.; Rudat, J.; Ochsenreither, K.; Syldatk, C.
2021. RSC Advances, 11 (54), 34235–34244. doi:10.1039/D1RA06190A
Growth optimization and identification of an ω-transaminase by a novel native PAGE activity staining method in a Bacillus sp. strain BaH isolated from Iranian soil
Gord Noshahri, N.; Fooladi, J.; Engel, U.; Muller, D.; Kugel, M.; Gorenflo, P.; Syldatk, C.; Rudat, J.
2021. AMB Express, 11 (1), Art.-Nr.: 46. doi:10.1186/s13568-021-01207-7
2020
Optimization of glycolipid synthesis in hydrophilic deep eutectic solvents
Hollenbach, R.; Bindereif, B.; Van Der Schaaf, U. S.; Ochsenreither, K.; Syldatk, C.
2020. Frontiers in Bioengineering and Biotechnology, 8, Art.-Nr.: 382. doi:10.3389/fbioe.2020.00382
Evaluation of Downstream Processing, Extraction, and Quantification Strategies for Single Cell Oil Produced by the Oleaginous Yeasts Saitozyma podzolica DSM 27192 and Apiotrichum porosum DSM 27194
Gorte, O.; Hollenbach, R.; Papachristou, I.; Steinweg, C.; Silve, A.; Frey, W.; Syldatk, C.; Ochsenreither, K.
2020. Frontiers in Bioengineering and Biotechnology, 8, Article no: 355. doi:10.3389/fbioe.2020.00355
Interfacial and Foaming Properties of Tailor-Made Glycolipids—Influence of the Hydrophilic Head Group and Functional Groups in the Hydrophobic Tail
Hollenbach, R.; Völp, A. R.; Höfert, L.; Rudat, J.; Ochsenreither, K.; Willenbacher, N.; Syldatk, C.
2020. Molecules, 25 (17), 3797. doi:10.3390/molecules25173797
Pulsed Electric Field Treatment Promotes Lipid Extraction on Fresh Oleaginous Yeast Saitozyma podzolica DSM 27192
Gorte, O.; Nazarova, N.; Papachristou, I.; Wüstner, R.; Leber, K.; Syldatk, C.; Ochsenreither, K.; Frey, W.; Silve, A.
2020. Frontiers in Bioengineering and Biotechnology, 8, Article 575379. doi:10.3389/fbioe.2020.575379
Enzymatic synthesis of glucose monodecanoate in a hydrophobic deep eutectic solvent
Hollenbach, R.; Ochsenreither, K.; Syldatk, C.
2020. International journal of molecular sciences, 21 (12), Article no: 4342. doi:10.3390/ijms21124342
2019
Effects of a Simulated Acute Oil Spillage on Bacterial Communities from Arctic and Antarctic Marine Sediments
Rizzo, C.; Malavenda, R.; Gerçe, B.; Papale, M.; Syldatk, C.; Hausmann, R.; Bruni, V.; Michaud, L.; Lo Giudice, A.; Amalfitano, S.
2019. Microorganisms, 7 (12), Art. Nr.: 632. doi:10.3390/microorganisms7120632
Screening and comparative characterization of microorganisms from Iranian soil samples showing ω-transaminase activity toward a plethora of substrates
Noshahri, N. G.; Fooladi, J.; Syldatk, C.; Engel, U.; Heravi, M. M.; Mehrjerdi, M. Z.; Rudat, J.
2019. Catalysts, 9 (10), Article No.874. doi:10.3390/catal9100874
Deep Eutectic Solvents as Efficient Solvents in Biocatalysis
Pätzold, M.; Siebenhaller, S.; Kara, S.; Liese, A.; Syldatk, C.; Holtmann, D.
2019. Trends in biotechnology, 37 (9), 943–959. doi:10.1016/j.tibtech.2019.03.007
2018
The demosponge (Pallas, 1766) as a novel source of biosurfactant-producing bacteria
Rizzo, C.; Syldatk, C.; Hausmann, R.; Gerçe, B.; Longo, C.; Papale, M.; Conte, A.; De Domenico, E.; Michaud, L.; Lo Giudice, A.
2018. Journal of basic microbiology, 58 (6), 532–542. doi:10.1002/jobm.201700669
Integrated Process for the Enzymatic Production of Fatty Acid Sugar Esters Completely Based on Lignocellulosic Substrates
Siebenhaller, S.; Kirchhoff, J.; Kirschhöfer, F.; Brenner-Weiß, G.; Muhle-Goll, C.; Luy, B.; Haitz, F.; Hahn, T.; Zibek, S.; Syldatk, C.; Ochsenreither, K.
2018. Frontiers in Chemistry, 6, Article: 421. doi:10.3389/fchem.2018.00421
β-Phenylalanine Ester Synthesis from Stable β-Keto Ester Substrate Using Engineered ω-Transaminases
Buß, O.; Voss, M.; Delavault, A.; Gorenflo, P.; Syldatk, C.; Bornscheuer, U.; Rudat, J.
2018. Molecules, 23 (5), Article: 1211. doi:10.3390/molecules23051211
Lipase-Catalyzed Synthesis of Sugar Esters in Honey and Agave Syrup
Siebenhaller, S.; Gentes, J.; Infantes, A.; Muhle-Goll, C.; Kirschhöfer, F.; Brenner-Weiß, G.; Ochsenreither, K.; Syldatk, C.
2018. Frontiers in Chemistry, 6, Article: 24. doi:10.3389/fchem.2018.00024
High Quality Draft Genomes of the Type Strains Geobacillus thermocatenulatus DSM 730T, G. uzenensis DSM 23175T And Parageobacillus galactosidasius DSM 18751T
Ramaloko, W. T.; Koen, N.; Polliack, S.; Aliyu, H.; Lebre, P. H.; Mohr, T.; Oswald, F.; Zwick, M.; Zeigler, D. R.; Neumann, A.; Syldatk, C.; Cowan, D. A.; De Maayer, P.
2018. Journal of Genomics, 6, 20–23
2017
Sustainable carbon sources for microbial organic acid production with filamentous fungi
Dörsam, S.; Fesseler, J.; Gorte, O.; Hahn, T.; Zibek, S.; Syldatk, C.; Ochsenreither, K.
2017. Biotechnology for biofuels, 10 (1), 242. doi:10.1186/s13068-017-0930-x
Beechwood carbohydrates for enzymatic synthesis of sustainable glycolipids
Siebenhaller, S.; Hajek, T.; Muhle-Goll, C.; Himmelsbach, M.; Luy, B.; Kirschhöfer, F.; Brenner-Weiß, G.; Hahn, T.; Zibek, S.; Syldatk, C.
2017. Bioresources and Bioprocessing, 4 (1), Art.Nr. 25. doi:10.1186/s40643-017-0155-7
Toward a cell-free hydantoinase process : screening for expression optimization and one-step purification as well as immobilization of hydantoinase and carbamoylase
Slomka, C.; Späth, G. P.; Lemke, P.; Skoupi, M.; Niemeyer, C. M.; Syldatk, C.; Rudat, J.
2017. AMB express, 7 (1), Art. Nr. 122. doi:10.1186/s13568-017-0420-3
Rouxiella badensis sp. nov. and Rouxiella silvae sp. nov. isolated from peat bog soil and emendation description of the genus Rouxiella
Fléche-Matéos, A. L.; Kügler, J. H.; Hansen, S. H.; Syldatk, C.; Hausmann, R.; Lomprez, F.; Vandenbogaert, M.; Manuguerra, J.-C.; Grimont, P. A. D.
2017. International journal of systematic and evolutionary microbiology, 67 (5), 1255–1259. doi:10.1099/ijsem.0.001794
Sustainable enzymatic synthesis of glycolipids in a deep eutectic solvent system
Siebenhaller, S.; Muhle-Goll, C.; Luy, B.; Kirschhöfer, F.; Brenner-Weiss, G.; Hiller, E.; Günther, M.; Rupp, S.; Zibek, S.; Syldatk, C.
2017. Journal of molecular catalysis / B, 133, 281–287. doi:10.1016/j.molcatb.2017.01.015
2016
Evaluation of Pyrolysis Oil as Carbon Source for Fungal Fermentation
Dörsam, S.; Kirchhoff, J.; Bigalke, M.; Dahmen, N.; Syldatk, C.; Ochsenreither, K.
2016. Frontiers in microbiology, 7, Art.Nr. 2059. doi:10.3389/fmicb.2016.02059
Microbial rhamnolipids
Henkel, M.; Müller, M. M.; Hörmann, B.; Syldatk, C.; Hausmann, R.
2016. Handbook of carbohydrate-modifying biocatalysts. Hrsg.: P. Grunwald, Pan Stanford Publishing. doi:10.4032/9789814669795
Novel insights into biosynthesis and uptake of rhamnolipids and their precursors
Wittgens, A.; Kovacic, F.; Müller, M. M.; Gerlitzki, M.; Santiago-Schübel, B.; Hofmann, D.; Tiso, T.; Blank, L. M.; Henkel, M.; Hausmann, R.; Syldatk, C.; Wilhelm, S.; Rosenau, F.
2016. Applied microbiology and biotechnology, 101 (7), 2865–2878. doi:10.1007/s00253-016-8041-3
Effect of spacer modification on enzymatic synthetic and hydrolytic activities of immobilized trypsin
Andre, J.; Saleh, D.; Syldatk, C.; Hausmann, R.
2016. Journal of molecular catalysis / B, 125, 88–96. doi:10.1016/j.molcatb.2016.01.003
Transaminases and their applications
Dold, S.-M.; Syldatk, C.; Rudat, J.
2016. Green biocatalysis. Ed.: R. Patel, 715–746, Wiley-VCH Verlag. doi:10.1002/9781118828083.ch29
Enzymatische Synthese von Biotensiden aus der Cellulosefraktion des Organosolvprozesses
Siebenhaller, S.; Hajek, T.; Zibek, S.; Syldatk, C.
2016. Chemie - Ingenieur - Technik, 88 (9), 1412 / V19.07. doi:10.1002/cite.201650171
Production strategies and applications of microbial single cell oils
Ochsenreither, K.; Glück, C.; Stressler, T.; Fischer, L.; Syldatk, C.
2016. Frontiers in microbiology, 7, 1539. doi:10.3389/fmicb.2016.01539
Substitution of the native srfA promoter by constitutive P-veg in two B. subtilis strains and evaluation of the effect on Surfactin production
Willenbacher, J.; Mohr, T.; Henkel, M.; Gebhard, S.; Mascher, T.; Syldatk, C.; Hausmann, R.
2016. Journal of Biotechnology, 224, 14–17. doi:10.1016/j.jbiotec.2016.03.002
Sequential Mixed Cultures : From Syngas to Malic Acid
Oswald, F.; Dörsam, S.; Veith, N.; Zwick, M.; Neumann, A.; Ochsenreither, K.; Syldatk, C.
2016. Frontiers in microbiology, 7, 891. doi:10.3389/fmicb.2016.00891
Stereoselective synthesis of β-amino acids by hydrolysis of an aryl-substituted dihydropyrimidine by hydantoinases
Engel, U.; Syldatk, C.; Rudat, J.
2016. Practical Methods for Biocatalysis and Biotransformations 3. Ed.: J. Whittall, John Wiley and Sons
2015
Biosurfactant activity, heavy metal tolerance and characterization of Joostella strain A8 from the Mediterranean polychaete Megalomma claparedei (Gravier, 1906)
Rizzo, C.; Michaud, L.; Graziano, M.; De Domenico, E.; Syldatk, C.; Hausmann, R.; Lo Giudice, A.
2015. Ecotoxicology, 24 (6), 1294–1304. doi:10.1007/s10646-015-1504-y
Immobilization of trypsin in organic and aqueous media for enzymatic peptide synthesis and hydrolysis reactions
Stolarow, J.; Heinzelmann, M.; Yeremchuk, W.; Syldatk, C.; Hausmann, R.
2015. BMC Biotechnology, 15 (1), 77. doi:10.1186/s12896-015-0196-y
Glycolipids produced by Rouxiella sp. DSM 100043 and isolation of the biosurfactants via foam-fractionation
Kügler, J. H.; Muhle-Goll, C.; Hansen, S. H.; Völp, A. R.; Kirschhöfer, F.; Kühl, B.; Brenner-Weiss, G.; Luy, B.; Syldatk, C.; Hausmann, R.
2015. AMB express, 5 (1), 82/1–11. doi:10.1186/s13568-015-0167-7
Chemical synthesis and enzymatic, stereoselective hydrolysis of a functionalized dihydropyrimidine for the synthesis of β-amino acids
Slomka, C.; Zhong, S.; Fellinger, A.; Engel, U.; Syldatk, C.; Bräse, S.; Rudat, J.
2015. AMB Express, 5 (1), 85. doi:10.1186/s13568-015-0174-8
Hydrolysis of Hydantoins, Dihydropyrimidines, and Related Compounds
Slomka, C.; Engel, U.; Syldatk, C.; Rudat, J.
2015. Biocatalysis in Organic Synthesis 1. Ed.: K. Faber, 373–414, Thieme Gruppe
Enhancement of Surfactin Yield by Improving the Medium Composition and Fermentation Process
Willenbacher, J.; Yeremchuk, W.; Mohr, T.; Syldatk, C.; Hausmann, R.
2015. AMB Express, 5 (1), Article Nr. 57, 9 S. doi:10.1186/s13568-015-0145-0
Foam-free Production of Surfactin via Anerobic Fermentation of Bacillus subtilis DSM 10T
Willenbacher, J.; Rau, J.-T.; Rogalla, J.; Syldatk, C.; Hausmann, R.
2015. AMB Express, 5 (1), 21/1–9. doi:10.1186/s13568-015-0107-6
Extracellular aromatic biosurfactant produced by Tsukamurella pseudospumae and T. spumae during growth on n-hexadecane
Kügler, J. H.; Kraft, A.; Heißler, S.; Muhle-Goll, C.; Luy, B.; Schwack, W.; Syldatk, C.; Hausmann, R.
2015. Journal of Biotechnology, 211, 107–114. doi:10.1016/j.jbiotec.2015.06.424
Biosurfactant production by Arctic and Antarctic bacteria growing on hydrocarbons
Malavenda, R.; Rizzo, C.; Michaud, L.; Gerçe, B.; Bruni, V.; Syldatk, C.; Hausmann, R.; Lo Giudice, A.
2015. Polar biology, 38 (10), 1565–1574. doi:10.1007/s00300-015-1717-9
The Prospects for the Production of Rhamnolipids on Renewable Resources: Evaluation of Novel Feedstocks and Perspectives of Strain Engineering
Henkel, M.; Syldatk, C.; Hausmann, R.
2015. Biosurfactants : production and utilization; processes, technologies, and economics. Ed.: N. Kosaric, 83–100, CRC Press. doi:10.1201/b17599-8
Bioreactors for the Production of Biosurfactants
Beuker, J.; Syldatk, C.; Hausmann, R.
2015. Biosurfactants : production and utilization; processes, technologies, and economics. Ed.: N. Kosaric, 117–128, CRC Press. doi:10.1201/b17599-10
Types and Classification of Microbial Surfactants
Hausmann, R.; Syldatk, C.
2015. Biosurfactants : production and utilization; processes, technologies, and economics. Ed.: N. Kosaric, 3–18, CRC Press. doi:10.1201/b17599-3
Lipase-catalyzed synthesis of glucose-6-O-hexanoate in deep eutectic solvents
Pöhnlein, M.; Ulrich, J.; Kirschhöfer, F.; Nusser, M.; Muhle-Goll, C.; Kannengiesser, B.; Brenner-Weiß, G.; Luy, B.; Liese, A.; Syldatk, C.; Hausmann, R.
2015. European journal of lipid science and technology, 117 (2), 161–166. doi:10.1002/ejlt.201400459
Enzymatic synthesis and modification of surface-active glycolipids
Pöhnlein, M.; Syldatk, C.; Lang, S.; Hausmann, R.
2015. Special Issue : Fats and Oils as Renewable Feedstock for the Chemical Industry, 117 (2), 145–155. doi:10.1002/ejlt.201400418
Teaching bioprocess engineering to undergraduates : Multidisciplinary hands-on training in a one-week practical course
Henkel, M.; Zwick, M.; Beuker, J.; Willenbacher, J.; Baumann, S.; Oswald, F.; Neumann, A.; Siemann-Herzberg, M.; Syldatk, C.; Hausmann, R.
2015. Biochemistry and Molecular Biology Education, 43 (3), 189–202. doi:10.1002/bmb.20860
Development of a microtiter plate-based assay for the detection of lipase-catalyzed transesterifications in organic solvents
Pöhnlein, M.; Finkbeiner, T.; Syldatk, C.; Hausmann, R.
2015. Biotechnology letters, 37 (3), 705–710. doi:10.1007/s10529-014-1721-0
Surfactants tailored by the class Actinobacteria
Kügler, J. H.; Le Roes-Hill, M.; Syldatk, C.; Hausmann, R.
2015. Frontiers in Microbiology, 6 (212), 1–23. doi:10.3389/fmicb.2015.00212
Micromagnetic porous and non-porous biocatalyst carriers
Stolarow, J.; Gerce, B.; Syldatk, C.; Magario, I.; Morhardt, C.; Franzreb, M.; Hausmann, R.
2015. Industrial Biocatalysis Singapore. Ed.: P. Grunwald, 521–552, Pan Stanford Publ
2014
The Hydantoinase Process: Recent developments for the production of non-canonical amino acids
Engel, U.; Rudat, J.; Syldatk, C.
2014. Industrial biocatalysis. Ed.: P. Grunwald, Chapter 22, 817–862, Pan Stanford Publ
Cationic heterooligopeptides by ficain-catalyzed co-oligomerization of lysine and methionine ethylesters
Andre, M.; Kühl, B.; Brenner-Weiss, G.; Syldatk, C.; Rudat, J.
2014. Journal of peptide science, 20, 625–629. doi:10.1002/psc.2639
Enzymatic synthesis of amino sugar fatty acid esters
Pöhnlein, M.; Slomka, C.; Kukharenko, O.; Gärtner, T.; Wiemann, L. O.; Sieber, V.; Syldatk, C.; Hausmann, R.
2014. European journal of lipid science and technology, 116 (4), 423–428. doi:10.1002/ejlt.201300380
Process characterization and influence of alternative carbon sources and carbon-to-nitrogen ratio on organic acid production by Aspergillus oryzae DSM 1863
Ochsenreither, K.; Fischer, C.; Neumann, A.; Syldatk, C.
2014. Applied Microbiology and Biotechnology, 98 (12), 5449–5460. doi:10.1007/s00253-014-5614-x
Trehalose lipid biosurfactants produced by the actinomycetes Tsukamurella spumae and T. pseudospumae
Kügler, J. H.; Muhle-Goll, C.; Kühl, B.; Kraft, A.; Heinzler, R.; Kirschhöfer, F.; Henkel, M.; Wray, V.; Luy, B.; Brenner-Weiss, G.; Lang, S.; Syldatk, C.; Hausmann, R.
2014. Applied microbiology and biotechnology, 98 (21), 8905–8915. doi:10.1007/s00253-014-5972-4
Evaluation of different Bacillus strains in respect of their ability to produce Surfactin in a model fermentation process with integrated foam fractionation
Willenbacher, J.; Zwick, M.; Mohr, T.; Schmid, F.; Syldatk, C.; Hausmann, R.
2014. Applied microbiology and biotechnology, 98 (23), 9623–9632. doi:10.1007/s00253-014-6010-2
Combination of algae and yeast fermentation for an integrated process to produce single cell oils
Dillschneider, R.; Schulze, I.; Neumann, A.; Posten, C.; Syldatk, C.
2014. Applied Microbiology and Biotechnology, 98 (18), 7793–7802. doi:10.1007/s00253-014-5867-4
Characterization of newly isolated oleaginous yeasts - Cryptococcus podzolicus, Trichosporon porosum and pichia segobiensis
Schulze, I.; Hansen, S.; Großhans, S.; Rudszuck, T.; Ochsenreither, K.; Syldatk, C.; Neumann, A.
2014. AMB Express, 4 (24), 1–10. doi:10.1186/s13568-014-0024-0
Long-chain polyesters and polyamides from biochemically derived fatty acids
Kolb, N.; Winkler, M.; Syldatk, C.; Meier, M. A. R.
2014. European polymer journal, 51, 159–166. doi:10.1016/j.eurpolymj.2013.11.007
Kinetic modeling of rhamnolipid production by Pseudomonas aeruginosa PAO1 including cell density-dependent regulation
Henkel, M.; Schmidberger, A.; Vogelbacher, M.; Kühnert, C.; Beuker, J.; Bernard, T.; Schwartz, T.; Syldatk, C.; Hausmann, R.
2014. Applied Microbiology and Biotechnology, 98 (16), 7013–7025. doi:10.1007/s00253-014-5750-3
2013
Kinetic modeling of the time course of N-butyryl-homoserine lactone concentration during batch cultivations of Pseudomonas aeruginosa PAO1
Henkel, M.; Schmidberger, A.; Kühnert, C.; Beuker, J.; Bernard, T.; Schwartz, T.; Syldatk, C.; Hausmann, R.
2013. Applied microbiology and biotechnology, 97 (17), 7607–7616. doi:10.1007/s00253-013-5024-5
Production of Microbial Rhamnolipid by Pseudomonas Aeruginosa MM1011 for Ex Situ Enhanced Oil Recovery
Amani, H.; Müller, M. M.; Syldatk, C.; Hausmann, R.
2013. Applied Biochemistry and Biotechnology, 170 (5), 1080–1093. doi:10.1007/s12010-013-0249-4
Lipase-catalyzed acylation of microbial mannosylerythritol lipids (biosurfactants) and their characterization
Recke, V. K.; Beyrle, C.; Gerlitzki, M.; Hausmann, R.; Syldatk, C.; Wray, V.; Tokuda, H.; Suzuki, N.; Lang, S.
2013. Carbohydrate Research, 373, 82–88. doi:10.1016/j.carres.2013.03.013
Influence of salinity and temperature on the activity of biosurfactants by polychaete-associated isolates
Rizzo, C.; Michaud, L.; Hörmann, B.; Gerce, B.; Syldatk, C.; Hausmann, R.; De Domenico, E.; Giudice, A. L.
2013. Environmental Science and Pollution Research, 21 (4), 2988–3004. doi:10.1007/s11356-013-2259-8
Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines)
Perzborn, M.; Syldatk, C.; Rudat, J.
2013. AMB Express, 3 (1), 12 S. doi:10.1186/2191-0855-3-51
Separation of Cyclic Dipeptides (Diketopiperazines) from Their Corresponding Linear Dipeptides by RP-HPLC and Method Validation
Perzborn, M.; Syldatk, C.; Rudat, J.
2013. Chromatography research international, 2013, 310269. doi:10.1155/2013/310269
2012
Influence of pH and carbon to nitrogen ratio on mycotoxin production by Alternaria alternata in submerged cultivation
Brzonkalik, K.; Hümmer, D.; Syldatk, C.; Neumann, A.
2012. AMB Express, 2 (1), ArticleNr. 28. doi:10.1186/2191-0855-2-28
Rhamnolipids - next generation surfactants?
Müller, M. M.; Kügler, J. H.; Henkel, M.; Gerlitzki, M.; Hörmann, B.; Pöhnlein, M.; Syldatk, C.; Hausmann, R.
2012. Journal of Biotechnology, 162 (4), 366–380. doi:10.1016/j.jbiotec.2012.05.022
Rhamnolipids as biosurfactants from renewable resources: concepts for next-generation rhamnolipid production
Henkel, M.; Müller, M. M.; Kügler, J. H.; Lovaglio, R. B.; Contiero, J.; Syldatk, C.; Hausmann, R.
2012. Process Biochemistry, 47 (8), 1207–1219. doi:10.1016/j.procbio.2012.04.018
Transaminases for the synthesis of enantiopure beta-amino acids
Rudat, J.; Brucher, B.; Syldatk, C.
2012. AMB Express, 2 (1), 11. doi:10.1186/2191-0855-2-11
Stereoselective hydrolysis of aryl-substituted dihydropyrimidines by hydantoinases
Engel, U.; Syldatk, C.; Rudat, J.
2012. Applied microbiology and biotechnology, 94 (5), 1221–1231. doi:10.1007/s00253-011-3691-7
Novel amidases of two Aminobacter sp. strains: Biotransformation experiments and elucidation of gene sequences
Engel, U.; Syldatk, C.; Rudat, J.
2012. AMB express, 2 (1), 33. doi:10.1186/2191-0855-2-33
2011
Process development for the elucidation of mycotoxin formation in Alternaria alternata
Brzonkalik, K.; Herrling, T.; Syldatk, C.; Neumann, A.
2011. AMB Express, 1, 27. doi:10.1186/2191-0855-1-27
Existing Value Chains
Syldatk, C.; Schaub, G.; Schulze, J.; Ernst, D.; Neumann, A.
2011. Renewable raw materials : new feedstocks for the chemical industry. Ed.: R. Ulber, Chapter 5, Wiley-VCH Verlag. doi:10.1002/9783527634194.ch5
Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440
Wittgens, A.; Tiso, T.; Arndt, T. T.; Wenk, P.; Hemmerich, J.; Müller, C.; Wichmann, R.; Kupper, B.; Zwick, M.; Wilhelm, S.; Hausmann, R.; Syldatk, C.; Rosenau, F.; Blank, L. M.
2011. Microbial Cell Factories, 10, 80. doi:10.1186/1475-2859-10-80
Differences Between Bacterial Communities Associated with the Surface or Tissue of Mediterranean Sponge Species
Gerce, B.; Schwartz, T.; Syldatk, C.; Hausmann, R.
2011. Microbial ecology, 61 (4), 769–782. doi:10.1007/s00248-011-9802-2
The influence of different nitrogen and carbon sources on mycotoxin production in Alternaria alternata
Brzonkalik, K.; Herrling, T.; Syldatk, C.; Neumann, A.
2011. International Journal of Food Microbiology, 147 (2), 120–126. doi:10.1016/j.ijfoodmicro.2011.03.016
Evaluation of rhamnolipid production capacity of Pseudomonas aeruginosa PAO1 in comparison to the rhamnolipid over-producer strains DSM 7108 and DSM 2874
Müller, M. M.; Hormann, B.; Kugel, M.; Syldatk, C.; Hausmann, R.
2011. Applied microbiology and biotechnology, 89 (3), 585–592. doi:10.1007/s00253-010-2901-z
2010
Synthesis of aromatic beta-amino-acid with new cyclic amidases
Bretschneider, U.; Syldatk, C.; Rudat, J.
2010. Chemie Ingenieur Technik, 82 (1-2), 161–165
Microbial conversion of B-Phenyl-alanine using new transaminase
Brucher, B.; Syldatk, C.; Rudat, J.
2010. Chemie Ingenieur Technik, 82, 155–160
Screening Concepts for the Isolation of Biosurfactant Producing Microorganisms
Walter, V.; Syldatk, C.; Hausmann, R.
2010. Biosurfactants, Section I., Ed.: R. Sen, 1–13, Springer-Verlag. doi:10.1007/978-1-4419-5979-9_1
Enantioseparation of Aromatic beta(A3)-Amino acid by Precolumn Derivatization with o-Phthaldialdehyde and N-Isobutyryl-l-cysteine
Brucher, B.; Rudat, J.; Syldatk, C.; Vielhauer, O.
2010. Chromatographia, 71 (11-12), 1063–1067. doi:10.1365/s10337-010-1578-x
Rhamnolipid production by Burkholderia plantarii DSM 9509(T)
Hörmann, B.; Müller, M. M.; Syldatk, C.; Hausmann, R.
2010. European Journal of Lipid Science and Technology, 112 (6), 674–680. doi:10.1002/ejlt.201000030
Microbial Biosurfactants
Syldatk, C.; Hausmann, R.
2010. European Journal of Lipid Science and Technology, 112 (6), 615–116. doi:10.1002/ejlt.201000294
Identification of an Aliphatic Epoxide and the Corresponding Dihydrodiol as Novel Congeners of Zearalenone in Cultures of Fusarium graminearum
Pfeiffer, E.; Hildebrand, A.; Becker, C.; Schnattinger, C.; Baumann, S.; Rapp, A.; Goesmann, H.; Syldatk, C.; Metzler, M.
2010. Journal of agricultural and food chemistry, 58, 12055–12062. doi:10.1021/jf1022498
Pseudomonas aeruginosa PAO1 as a model for rhamnolipid production in bioreactor systems
Müller, M. M.; Hörmann, B.; Syldatk, C.; Hausmann, R.
2010. Applied microbiology and biotechnology, 87 (3), 167–174. doi:10.1007/s00253-010-2513-7
2009
Kinetic Analysis and Modeling of the Liquid-Liquid Conversion of Emulsified di-Rhamnolipids by Naringinase From Penicillium decumbens
Magario, I.; Viclhauer, O.; Neumann, A.; Hausmann, R.; Syldatk, C.
2009. Biotechnology and Bioengineering, 102 (1), 9–19. doi:10.1002/bit.22057.
Deactivation Kinetics and Response Surface Analysis of the Stability of alpha-l-Rhamnosidase from Penicillium decumbens
Magario, I.; Neumann, A.; Oliveros, E.; Syldatk, C.
2009. Applied Biochemistry and Biotechnology / Part A, 152 (1), 29–41. doi:10.1007/s12010-008-8204-5
Evaluation of enzyme carriers as biocatalysts for the conversion of emulsified rhamnolipids
Magario, I.; Neumann, A.; Vielhauer, O.; Syldatk, C.; Hausmann, R.
2009. Biocatalysis and biotransformation, 27 (4), 237–245. doi:10.1080/10242420903042619
Morphological, Bacterial, and Secondary Metabolite Changes of Aplysina aerophoba upon Long-Term Maintenance Under Artificial Conditions
Gerce, B.; Schwartz, T.; Voigt, M.; Rühle, S.; Kirchen, S.; Putz, A.; Proksch, P.; Obst, U.; Syldatk, C.; Hausmann, R.
2009. Microbial ecology, 58 (4), 865–878. doi:10.1007/s00248-009-9560-6
2008
Non-porous magnetic micro-particles: Comparison to porous enzyme carriers for a diffusion rate-controlled enzymatic conversion
Magario, I.; Neumann, A.; Syldatk, C.; Hausmann, R.
2008. Journal of Biotechnology, 134 (1-2), 72–78. doi:10.1016/j.jbiotec.2007.12.001
Zeta potential measurement as a diagnostic tool in enzyme immobilisation
Schultz, N.; Metreveli, G.; Franzreb, M.; Frimmel, F. H.; Syldatk, C.
2008. Colloids and Surfaces / B, 66 (1), 39–44
Effect of emulsified feeding of oily substrate via submerged ceramic membranes on surfactant production in Pseudomonas aeruginosa fermentation
Dhariwal, A.; Mohrdieck, M.; Leitermann, F.; Arjol, I. M.; Manresa, A.; Syldatk, C.; Janke, H. D.; Chmiel, H.
2008. Bioprocess and Biosystems Engineering, 31 (5), 401–409
Zeta potential measurement as a diagnostic tool in enzyme immobilisation. Erratum to ’Zeta potential measurement as a diagnostic tool in enzyme immobilisation’
Schultz, N.; Metreveli, G.; Franzreb, M.; Frimmel, F. H.; Syldatk, C.
2008. Colloids and Surfaces B, 66(2008) S.39-44, 66(2008) S.304 (Erratum) DOI:10.1016/j.colsurfb.2008.08.001. doi:10.1016/j.colsurfb.2008.05.004
2007
Spectrophotometric assay for online measurement of the activity of lipase immobilised on micro-magnetic particles
Schultz, N.; Hobley, T. J.; Syldatk, C.
2007. Biotechnology Letters, 29 (3), 365–371. doi:10.1007/s10529-006-9253-x
Stereoselective Prostereogenic 3-Oxo Ester Reduction Mediated by a Novel Yeast Alcohol Dehydrogenase Derived from Kluyveromyces marxianus CBS 6556
Perrone, M. G.; Santandrea, E.; Scilimati, A.; Syldatk, C.
2007. Advanced Synthesis & Catalysis, 349 (7), 1111–1118. doi:10.1002/adsc.200600379
Integrated processing and multiple re-use of immobilised lipase by magnetic separation technology
Schultz, N.; Syldatk, C.; Franzreb, M.; Hobley, T. J.
2007. Journal of Biotechnology, 132, 202–208. doi:10.1016/j.jbiotec.2007.05.029
Integral continuous microbial rhamnolipid production
Heyd, M.; Franzreb, M.; Hausmann, R.; Syldatk, C.; Berensmeier, S.
2007. Journal of Biotechnology, 131, S77. doi:10.1016/j.jbiotec.2007.07.134
Integral continuous microbial rhamnolipid production
Heyd, M.; Franzreb, M.; Hausmann, R.; Syldatk, C.; Berensmeier, S.
2007. 13th European Congress on Biotechnology (ECB13), Barcelona, E, September 16-19, 2007 Journal of Biotechnology, 131(2007) (Abstract)
Integral continuous microbial rhamnolipid production
Heyd, M.; Franzreb, M.; Hausmann, R.; Syldatk, C.; Berensmeier, S.
2007. Journal of Biotechnology, 13th European Congress on Biotechnology (ECB13), Barcelona, E, September 16-19, 2007, (Abstract), 131, S77
2006
Microbial production of single-cell protein from deproteinized whey concentrates
Schultz, N.; Chang, L.; Hauck, A.; Reuss, M.; Syldatk, C.
2006. Applied Microbiology and Biotechnology, 69 (5), 515–520. doi:10.1007/s00253-005-0012-z
Biomass recycling from a riboflavin cultivation with B. subtilis: lysis, extract production and testing as substrate in riboflavin cultivation
Bretz, K.; Ilijevic, S.; Grüneberg, M.; Becker, U.; Syldatk, C.
2006. Biotechnology and Bioengineering, 95 (6), 1023–1031
The utilization of renewable resources in German industrial production
Busch, R.; Hirth, T.; Liese, A.; Nordhoff, S.; Puls, J.; Pulz, O.; Sell, D.; Syldatk, C.; Ulber, R.
2006. Biotechnology journal, 1 (7-8), 770–776. doi:10.1002/biot.200600057
Distribution of hydantoinase activity in bacterial isolates from geographically distinct environmental sources
Durr, R.; Vielhauer, O.; Burton, S. G.; Cowan, D. A.; Punal, A.; Brandao, P. F. B.; Bull, A. T.; Syldatk, C.
2006. Journal of molecular catalysis / B, 39, 160–165. doi:10.1016/j.molcatb.2006.01.017
Engler-Bunte-Institut der Universität Karlsruhe (TH) und Technologiezentrum Wasser (TZW), Karlsruhe, im Jahre 2005. Kapitel 4-6
Bockhorn, H.; Braun, A. M.; Frimmel, F. H.; Kühn, W.; Reimert, R.; Syldatk, C.
2006. GWF / Wasser, Abwasser, 147 (6), 455–461
Engler-Bunte-Institut der Universität Karlsruhe (TH) und Technologiezentrum Wasser (TZW), Karlsruhe, im Jahre 2005. Kapitel 1-3
Bockhorn, H.; Braun, A. M.; Frimmel, F. H.; Kühn, W.; Reimert, R.; Syldatk, C.
2006. GWF / Gas, Erdgas, 147 (6), 339–351
2005
Application of magnetic separation technology for recovery of immobilised lipases
Schultz, N.; Neumann, A.; Metreveli, G.; Franzreb, M.; Syldatk, C.
2005. 12th European Congress on Biotechnology, Copenhagen, DK, August 24-25, 2005 Journal of Biotechnology, 118(2005) Suppl.1, (Abstract)
Application of magnetic separation technology for recovery of immobilised lipases
Schultz, N.; Neumann, A.; Metreveli, G.; Franzreb, M.; Syldatk, C.
2005. Journal of Biotechnology, 12th European Congress on Biotechnology, Copenhagen, DK, August 24-25, 2005, Suppl.1, (Abstract), 118, S60
2004
Cloning of D-specific Hydantoin Utilization Genes from Arthrobacter crystallopoietes
Werner, M.; Las Heras Vazques, F. J.; Fritz, C.; O. Vielhauer, O.; Siemann-Herzberg, M.; Altenbuchner, J.; Syldatk, C.
2004. Engineering in Life Sciences, 4 (6), 563–572. doi:10.1002/elsc.200402158
Bioconversion of D,L-tert-leucine Nitrile to D-tert-leucine by Recombinant Cells expressing Nitrile Hydratase and D-selective Amidase
Brandão, P. F. B.; Verseck, S.; Syldatk, C.
2004. Engineering in Life Sciences, 4 (6), 547–556. doi:10.1002/elsc.200402153
Diastereo- and enantioselevtive bioreduction of ethyl 2-(chlorophenoxy)-3-oxobutanoate clofibrate analogues by Klyveromyces marxianus and other whole cell bioctalysts
Perrone, M. G.; Santandrea, E.; Scilimati, A.; Syldatk, C.; Tortorella, V.; Capitelli, F.; Bertolasi, V.
2004. Tetrahedron asymmetry, 15, 3511–3517
2003
An integrated microbial/enzymatic process for production of rhamnolipids and L-(+)-rhamnose from rapeseed oil with Pseudomonas sp. DSM 2874
Klaus Trummler, K.; Effenberger, F.; Syldatk, C.
2003. European Journal of Lipid Science and Technology, 105 (10), 563–571. doi:10.1002/ejlt.200300816
1993
Synthesis of acetyldimethyl(phenyl)silane and its enantioselective conversion into (R)-(1-hydroxyethyl)dimethyl(phenyl)silane by plant cell suspension cultures of Symphytum L. and Ruta graveolens L
Tacke, R.; Wagner, S. A.; Brakmann, S.; Wuttke, F.; Eilert, U.; Fischer, L.; Syldatk, C.
1993. J. of organomet. chem. 458 (1993) S. 13-17
1991
Synthesis and enantioselective enzymatic hydrolysis of rac-dimethylphenyl[1- (phenylacetamido)ethyl]silane
Hengelsberg, H.; Tacke, R.; Fritsche, K.; Syldatk, C.; Wagner, F.
1991. J. of organomet. chem. 415 (1991) S. 39-45
Stereoselective microbial reduction of racemic acetyl(t-butyl)methylphenylsilane by Trigonopsis variabilis (DSM 70714) and Corynebacterium dioxydans (ATCC 21766)
Tacke, R.; Brakmann, S.; Wuttke, F.; Fooladi, J.; Syldatk, C.; Schomburg, D.
1991. J. of organomet. chem. 403 (1991) S. 29-41